21c Museum Hotel Lexington – Boutique Hotel, Art Museum & Culinary Destination
Location:
167 West Main Street
Lexington, KY 40507
21c Museum Hotel Lexington is a premier 88‑room boutique hotel that seamlessly blends contemporary art, culture, and fine dining. As a dynamic museum and cultural hub, it offers curated exhibitions and community‑focused programming that showcase local talent and international artists alike. Guests dine at Lockbox, the on‑site restaurant helmed by executive chef Cody DeRosett, where inventive Southern‑inspired cuisine meets a sophisticated atmosphere. Whether you’re a traveler seeking a unique stay or a local exploring downtown Lexington, 21c invites you to experience the iconic Blue Penguin and the vibrant artistic scene it proudly hosts.




